my advice is don't bother learning to play a left-handed guitar. if you're aspiring to be a lead player more than a rhythm player, it may help you to have your dominant hand on the fretboard, rather than holding the pick. it also keeps you from limiting yourself to what's available in left-handed models.
besides, i think guitars and basses are the only instruments that come in a left-handed design (well, other than drummers who set up their drums backwards).
i really think you'll be happier in the long run if you learn righty.
btw, Mattias 'IA' Eklundh is a lefty who plays righty, and i wouldn't say he's got any trouble....he even said in one of his clinics that he thinks of guitars played the normal way as "left-handed" for the reason i mentioned above.
that said, i'm primarily a rhythm player, and i love having the pick in my dominant hand.