Izotope Ozone 4 Ticks and clicks..

Sounds just like dropouts caused by unsynchronised ADAT devices (wrong clock). Are you positive it's because of ozone and not because it's recorded that way?
 
Good point..

JB try and run different audio through the same masterbus settings and see if the crackling/clicky noise is still there.
 
If it's the audio the dropout will occur at the same place. If it's your setup it will be random. I haven't heard of such issue with Ozone before.