I had this average RG 270, first non-shitty guitare I owned, and when I changed POWERSOUND stock pickups (great name, huh ?) for used dimarzio (Dual Sound aka Super Distortion with split/phase 4 wires and Air Norton on neck), it REALLY changed my tone for good, but be sure, your tone is :
-20 % guitar (so pickups could be 10 % of the whole chain)
-30 % amp
-50 % YOUR HANDS ! (a good musician sounds good, on crappy tools too)
Changing pickups did a good improvement on the 20 % of the guitar, but a new pickups, most of the time, will change your EQ response, and maybe improving feedback annoyance with distortion.
SO, what I would do is buying used pickups as I did back in the days, and for the floyd rose...too expensive for the guitar
-edit- and yes, you're right, wizard II neck is just perfect for modern players, what a great (and cheap) neck Ibanez use on a lot of their stuffs...I remember improving my techniques so well with this neck, it was so hard to play on another brand after that (it was my one and only guitar for years)
(percentages used in this post are my own interpretation, of course, it is not proven facts !)