It's very common on guitarist starting the songs with the tone, and so your head asks for a massive freq fill, but that's not the case if you're dealing with drums and bass guitar, all the instruments should fill the spectrum, the guitar just needs it's very own place, having different mono sources correctly panned gives a wider image than stereo sources everywhere, so i'd say get your amazing tone once you've got a good bass and decent drums filling the other areas, and yes, your guitar will most probably sound weak solo'd. I've learned that here, and it payed well, you have to really notice the bass doing something, bass is bass, guitar is guitar, but good bass + good guitar = cool tone. Hope it helps, it's all referenced from this fourm, and i can really say it works.