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Are neck-thrus desirable on guitars? I've never played one, but have always liked the idea of them - mostly seen it applied on basses.

Yeah they're generally considered the best option all round. The downside being if there's a bad neck injury the whole guitar is screwed. Pretty common on guitar too, I've 5-6 different neck through guitars here between me and my brother
 
meh as well, why is that one so appealing ? Isn't it a mega generic guitar with "meshuggah" in big letters ?

I love neck through, each time I go back to a screwed neck guitar I feel like something is wrong ! I never felt any difference in the snap or frequency balance, I didn't even though about it.
 
All that and then it has that Edge III fixed bridge. Oh come on.

I'm already set on the 8-string front anyway though, I <3 my fanned fret monster. I don't really get why you're hating on the laminated necks either, it's much more consistent in tone (almost no possibility of dead notes etc.), much stronger against climate changes and so on. My custom has a 7pc wenge/maple/bubinga neck and not once have I regretted it.

I don't really like neck throughs either, my custom 7 is one and the 8-string is bolt-on. Obviously the upper fret access of the 7-string rules, but it has less bite tonewise and somehow I feel there's a lack of dynamics and responsivity.
 
meh as well, why is that one so appealing ? Isn't it a mega generic guitar with "meshuggah" in big letters ?

I love neck through, each time I go back to a screwed neck guitar I feel like something is wrong ! I never felt any difference in the snap or frequency balance, I didn't even though about it.

Generic? It's a 29.4" scale neckthrough 8 string guitar that comes stock with an expensive Swedish bridge pickup. Not exactly generic by any means...

It's roughly the same specs as the guitars they have been using for many years. I say roughly only because I think the scale length is not identical. I thought their guitars were 30.5" scale? Maybe they experimented and liked 29.4" better. Also, their original guitars use a modified fixed bridge version of the edge lo-pro instead of this new bridge from the rg2228. Everything else about them is very similar.

List price is $80000, but actual retail price is going to be around $4800. The reason it's so high is because it's being made in the Sugi custom shop. The only other guitars that were made here were the UV77RE (Steve Vai), the JSBDG (Joe Satriani) and the PGMFRM1 (Paul Gilbert). Basically, Ibanez is honoring Meshuggah as one of their very top level artists.

I wouldn't buy it. I like EMGs, I use my neck pickup all the time, and I wouldn't spend that much money on a single guitar, but I think it's cool that Ibanez finally released it, and I would LOVE to play it. I think I would like the massive scale length. People have been asking for them to make these for a long time. Congrats to Fredrik and Marten.