Can someone indentify this comic

[The Unavoidable]

The last panel, where is it from? I've seen webcomics all around making fun of that panel, and there are several more on that site. Does anyone have a clue where it's from?

http://biggercheese.com/index.php?comic=755

 

[Metaltastic]

Ctrl-Alt-Delete (specifically the notorious miscarriage episode) - for an absolutely hysterical rip on it (well, webcomics in general, but specifically that), check out this entry by the one and only Yahtzee:

http://www.escapistmagazine.com/videos/view/zero-punctuation/108-Webcomics