Killzone.
You can't set mids, bass etc.. at 0.
The curve eq will quite make the sound similar to the source, but it will not "replace" entirely.
So it's better to record with your own settings, and after to apply a curve eq to paste with the "eq capture".
So in context it looks like this :
guitar --> sound card ----> amp sim with your usual settings ---> sir2 or voxengo boogex or whatever with an impulse ---> curve eq loaded in voxengo curve eq or assimilator or whatever.
This is the normal chain. but you can add a sneap C4 before if you want to minimalize the palmute noise.
Check out Dandelium's posts about sims and you'll find the best way to use it.
A question : what are your curve eq ? are they coming from bands you listen ?