As several people have said, my first impression is that the songs are actually quite good - definitely better than 'Christ Illusion' and probably better than most of the stuff on 'God Hates Us All' too. There's some melody, some proper riffs (rather than just atonal grind). Tom Araya sounds fantastic too, really varied and interesting - the middle section of 'Human Strain' is brilliant.
The mix isn't as bad as I'd been fearing, it's just very different to most of the stuff around now. The drums, bass and vocals sound fine (though I've never liked a Slayer kick sound, and this one keeps up that tradition), but the guitars do sound really odd. I'd say they're under-gained - at the start of 'Snuff' there's barely enough sustain to keep them going. And I don't know about the pickup/position choice; to my ears it they almost have that Tele sound to them. The only metal band I can think of with a similar tone and twang is Unsane, but they make it work and Slayer fail miserably.
The other weird thing is how dry it all is. Most bands spend ages trying to sound huge, especially with the drums, but this CD sounds really small close. Even the snare sounds bone dry. It's like they took Rubin's advice from 'Reign In Blood' about turning the 'verb down on the guitars and applied it to everything.
Steve