The biggest difference you will notice is in your gain, the 81/85 set has amazing gain. Listen to Zakk Wylde to hear the actual 81/85 set, or In Flames and Symphony X (Just to name a couple) to hear a pair of 81s. Of course, your amp will have a huge effect on your tone as well, so be careful there. To get the most out of that set, I would recommend either a Line 6 (HD-147, Spider II, Vetta), Peavey (5150, 5150 II, JSX), or Marshall (Mode Four, TSL). Chances are you will need a noise gate in order to get the most out of those pickups, so if you don't already have one, I suggest you invest in one in the near future. I am glad to be of any help!