Lo and Hi filters are not extreme.
Also, its impossible to tell you what to do, since you should eq with other mix elements...
That being said, I can`t tell you if those boosts and cuts will work... This is little processing for IR, IMO.
A tip I can give is to boost a frequency with a hi q (with other mix elements playing) and check what is colliding with the guitar sound or what is the guitar's sound frequency doing to other elements. Then you boost/cut the frequency.
Another tip is to let the guitars volume a bit quite and make them cut through the mix without moving the fader, just eqing.
Just don't overdo things.
Also, the boosts and cuts are also influenced by what you like or not on a sound.
There are some basic explanation on the Systematic Productions mix book. Check it out, It may help you!
Cheers!