I have been using Pod Farm 2 for much of my client work with results good enough to make the clients happy.
However I recently purchased TSE X50 v2 and I love it. I'm stoked for the next release.
I also bought ToneForge Menace from Joey Sturgis Tones. I have only used it on one song, so far, but the tone worked for that song/mix.
Use of Amplitube/Guitar Rig is rare for me. Guitar Rig I use more for FX, and it definitely shines in this area, although I did use it on rhythms for a hardcore project I did late last year. Amplitube I really just haven't found a use for but I know a lot of people speak highly of it. It's just not my go-to.
BIAS interests me a lot, I've messed with the demo of it and would like to dive into it some more. I've heard some great tones out of it, a buddy of mine switched to it for his main rhythm/jam tone and it's pretty sick. So I can see myself purchasing it pretty soon.