i know that with the delta drivers you can run multiple cards if you have enough pci slots.... i belive the drivers allow for up to 4 cards... at the left hand side of the driver mixer window you can choose wich card to look at etc.... you can also use say a delta 44 with a 66 if your just after more analogue ins/outs on the cheap..... even better look at the 1010 light.... it has no break out box but does have a crap load of ins and outs on phonos...
hope that helps mate
C