I havent heard the livewire pickups, but with EMGs, IMHO, I think the sound from the 5150 and XXX can be somewhat too compressed.
Maybe its just my preference, or something but it becames so squishy and flat.
My bandmate uses a XXX and when he uses his Explorer with the original R490 (or what they are called) Gibson pickups, it sounds more alive to when I use my guitar with EMGs into his amp.
Maybe It has to do with the guitar itself also, (Mahogany vs Alder) but if I were you I would try them out on a guitar in a store through a 5150 before you buy them.
Although I have heard that the Livewire shold be better than the EMGs in this regard.