Another thing that really affects the sound is the type of wood.
Cheap ibanez's are kinda hit and miss, my 200 euro one sounds pretty good actually.And that's why cheap Ibanez guitars sound so bad. Even loaded with EMG's.
All in all, I think Jacksons give you the most bang for your buck. My V is actually a low end model (22 fret dot inlays, and no tremolo, and the tone on that thing rocks!). I just scored a Jackson Warrior WRMG, with transparent black on Tiger maple, the body is Alder, came stock with EMG's an 81 and an 85, That guitar sounds SICK!! I love the tone on that guitar. The shape kinda reminds me of Chuck Shuldiner's BC Rich (RIP). If your considering EMG's I'd say go for it, you won't be disappointed!
I don't care for the fat necks on Jacksons, BC Rich.
Yes ESP's got fatter necks,just Kirk Hammet models got thinner necks