Hey! First of all, go over a DI track of yours with an amp sim (without playing the guitar, just by being the listener), then start off with the gain section: turn the gain down to ZERO, and then go slowly up with the gain til like 4, or 5. You dont want alot of gain, otherwise its just going to get muddy! Dont scoop your mids!!!! Sounds like you dumped all the mids there... good boosting area for guitars in the mids is around 2khz (just fool around a little with an EQ). Oh yeah, and dont forget to use a High pass filter and a Low pass filter! Especially to get rid of the "fizz" in the high end (maybe try setting your LPF at around 10-12khz...just try around, you´ll come up with something). Hope i could help you with this! Cheers