I've heard some nightmares through the touring crew circuit in the last couple of years and even had a friend turn down guitar teching for him b/c of the constant volatility. Obviously I can't/won't name names but barring some radical change it still seems to depend on which Dave you get. Hanging out with someone, working with someone, and working for someone are all radically different dynamics. I may be wrong and I certainly wouldn't discourage anyone from pursuing this but I would discourage people from relocating to work for a guy who is notoriously difficult to work with.
Whilst you have to sing the songs of whom brings the bread to your table, Mustaine isn't really harder to work with than your average boss - with the exception of that the artistic people often have a strong vision of how they want things to be. That's what's made them usually what they are and to stand out from the rest. It's called passion. Anyone who understands this is just fine. Mustaine, just as anyone else, will listen to other people and will not make anyone work as their slaves for 20hrs per day. But just as it is with many bosses, they have their on and off days. They're just as moody as anyone else. But just because they happen to run the show, people are very scared of their mood swings.
What comes to artistic people in general, most of us are sensitive and moody. You'll hear people complain about their working communities, about the working atmosphere and about their bosses the most in art related working communities and in the so called third sector jobs. NGO's and so on. There's many studies to prove this.
You'll also find the biggest amount of alcoholics and drug addicts working for these sectors.
This all is just to say you shouldn't believe everything you hear if you work in these fields. Hear say equals shit in here. As per usual, it's just about the chemistry.
Mustaine was surely overly difficult sometimes when he was out his head with drugs but nowadays he's a bit different.
Besides, he knows his way around the studio quite well as he has produced many albums so in many ways he'd probably be interesting to work with in a professional sense.
Also, knowing the job offered, the person would be working for other projects for a lot of the time as other bands use the studio as well. Mustaine wouldn't be around that much at all - and certainly not overseeing the day to day work.