I've been through them all and they all have their pros and cons. In a large corporate environment you're stuck with using IE still really for many reasons (largely compatability and support), although its better than its ever been. Hating on IE & MS is old, and its actually a more secure and better supported browser than safari. I used chrome for a while, found it the fastest of the lot but that doesnt come without reduced functionality. Firefox is king. They all need a good clean out every now and again though after they have installed their hordes of 3rd party plugins : D