My bandmate uses amp sims live and in practice. He posts here under the name if6was9. He basically runs through a firepod into his PC with the output going in a SS poweramp and into his cab. He only uses free ampsims for the job, he was using Wagner but has switched to some of the newer Nick Crow ones. People are always commenting on how interesting the setup is and how good it sounds. It so versatile a setup, you can get an amazing clean tone from it too by using loads of reverbs/delays and stuff.
Yeah thats me,
I run an A/b box splitting my guitar into the first 2 Di inputs on my firepod.
Getting a 2nd one to use with my di box to expand it to 3 sounds,
Clean, Rhythm and Solo, currently I use all three but can only use 2 per song.
It's class- you can have total control over your tone, I run Reaper and use the the Nick crow pre's. No cab sims- just straight out via a line out into a power amp and cab. All the plug ins I use are Freeware
It really shines for solo tone and clean stuff- I run a tempo delay that I can set to always be so many beats or fractions of a beat behind no matter what tempo I'm playing in- no tap tempo or anything. You can tailor everything as much as you can when mxing- I eq my delays to leave room for my main guitar to cut through without getting too clogged.
Also it's worth putting a little compression or a limiter on before the di hits your pre amp- if you're levels are low it'll keep em hitting the preamp at normal guitar levels. Setting relative levels between patchs is a breeze- you just move the fader!
Also I run Reatune on my screen during the gig so I can have a giant accurate tuner behind me- kicks ass!
I don't have a laptop though so I carry my desktop around with me- solid as a rock but I'm always worried its gonna get thrashed!
I love using my gear for slightly outside applications, I've started running completely FOH through my firepods via REAPER. It's class- you can go to town on everything- compress the vocals and then use an EQ to get right in there and bring down problem feedback frequencies- going in and doing each monitor and the main speakers separately. I've mixed a couple of gigs like this now and they've all turned out savage. I find it pretty fast too- didn't take me any longer than when I just use a regular mxing desk and its sooo much more flexible. I run the main mix through the control room monitors and run the monitors through line outs. I generall stick a limiter on the main out aswell set to about a Db shy of clipping so no matter how hard I hit my master bus it's not gonna clip and damage any speakers.
Biggest help is the stock Reaper EQ- as many bands as you want doing whatever you want instead of the clumsy wide Q and high low shelfs of most mid sized venue's desks. Once you get fancy with the routing the number of applications besides recording you can use your DAW set up for is crazy!!