is it a feedback loop caused by your monitoring. i'm not familiar with the firepod routing software but use the "firestudio" and ran into a similiar problem. Make sure you're not monitoring through the output that you are sending the DI signal out of.
Oh damn, good call, I forgot the FP had a mix knob like cheap crappy USB interfaces But I wonder if it sends the sound back through all 8 outputs, or just the 2 monitor outputs (and if that can be adjusted in the software control panel)
are you sure its not the cable thats connected to rmp box? i run the exact same set up you have, what type of cable do you have going into your rmp box from the firepod is the balanced or unbalanced/
I'm sorry but I don't think that would take care of the noise.
HOW TO PREP YOUR TRACKS TO BE REAMPED
MAKE SURE TO RECORD AT 24 BIT ... You're recording at 24 bit, so you have plenty of room before noise sets in.
One thing that I always do is run a long balanced cable to the reamp box and a short cable from the reamp box to the amp.
What I mean is don't keep the reamp next to the firepod and run a long unbalanced (instrument) cable all the way across the room.
Just a thought.