I don't think you'd need that for soloing - the Mesa should have more than enough gain; unless you wanted to just reshape and further compress the TS sound (which I would recommend if you've scooped the mids all out, as solo tones typically need some midrange to stand out) you wouldn't need it as much as you would for your rhythm sound.
As for the solo boost on your rhythm sound, I'd say no because (1) live, you've lost a LOT of dynamic control by using all of your tricks in one place and (2) in the studio, you have ABSOLUTELY NO NEED for that much gain in a rhythm sound - you shouldn't record rhythm guitar with more than 75% of the gain that sounds good in the room if you plan on multiple tracks. That's fizz, loss of clarity, and ear fatigue zone.
Jeff