I concur with Seditious for the most part - but I do wonder whether fashioning society around an 'everything can be improved / fixed' perspective, leads to an inability to accept and enjoy current, unmodified, states... I think a balance between striving for improvement and accepting what we have is to be valued.
my hope, going into such endeavors, is that they would ultimately lead to more self-acceptance, as there would be a lot less extremes in talents/looks/etc. within any such society which would give people a sense of expectations which are actually unrealistic for them to live up to. Undoubtedly Stephen Hawking's no Brad Pitt, and Brad Pitt will never be a Stephen Hawking, but they're able to accept 'I can't be good at everything', and I think that would transfer over, with a slight improvement. In that future, people can learn to accept 'well sure, some people are infinitely better than me, at -that-, but I don't need to feel bad about it, because it's not like I'm -nothing-' and they will, more than the average person now, have strengths of their own to be proud of, and learn to appreciate that, where as today there are ugly stupid hated annoying people everywhere, who, frankly, don't deserve to have as much self-esteem as they may have thanks to another's social or sexual poverty forcing them into welcoming such a person as better than nothing...
there is always a 'rich get richer' concern, and I think we'd be right to keep an eye on that, not at all because it's 'wrong' to do such things, or 'unfair' to others who miss out, but purely so that we don't end up with some form of cyborg racism against the inferior (frail, stupid, impulsive) lower-class community who's parents couldn't afford memory chips and creatine to enhance their child to skyrocket ahead in abilities... in other words, purely for pragmatic reasons.
Ultimately it would depend on someone's philosophy of values that their satisfaction with improvement and achievement rests, I don't think people would forever be dissatisfied with not being the best singer or hottest celebrity or smartest writer, there would be a level of comfort reached at which people can have the same lack of concern for the public opinion as many of us do now.
really, it seems it would be only in something like a communist culture rather than one like our own where people would be despised for not doing more when they're quite capable.
In summary, I think people could self-regulate any personal burden of the advances. There may be public opinion of a certain leaning, just as today we praise 'productive' people over the drug addict who enjoys himself, but there wouldn't be any significant peer pressure that would interrupt people's acceptance of their own life, having improved themselves to some level fit for an easy life; and it's only the threat of a greater division between 'they who excel' and 'they who merely survive' (and their own philosophical burden of their own worthlessness by comparison) which could be worsened; and while a society of 'the weak who don't accept their own weakness', where they could better themselves, would be a beautiful thing to inject into the idiot religious masses of today, upon people who have no hope of measuring up to a world of people more than just 'not extremely stupid', it could be dangerous.
I guess the question there comes is whether we should at all care about those people and their feelings, or accept that they're expendable and therefore no expense toward their betterment is necessary, and rather we can just better our surveillance to oppress any instinct toward crime fueled by their dissatisfaction with the life given them by the parents who chose, knowing perfectly well the world they'd be raising them in (---a hatred thus best directed at the parents for their selfishness really... but such people are never so sensible, are they).
There may be a lack of compassion in this (one I think philosophically deserved), but I think you and I agree, we don't at all need to talk about 'killing off a group of people' or something like that, merely negligence, the like the entire western world shows to every African, Indian, Chinese, etc. who is suffering poverty and sickness and all the rest
today... so realistically, it seems, certainly not sinister like 'wipe out the Jews', but further,
not even more heartless than the world we support today.
