E is either MDMA or MDA--it's another term for ecstasy (and the one my circle of friends uses exclusively). the only people i know who call it "X" are 40+ year old partyers.
Interesting. I kinda figured though, never fucked with it. The hardest I've done is coke, well, some chick gave me her exhallations of what she'd freebased, so I guess that's worse? I dunno. I'd rather just stick the two (unaltered) organics which are the shrooms, and w33d.