A poll here would require too many options.
1. Eastern Promises (voice over was dumb and clichéd in execution; but aside from this, near perfect)
2. Knocked Up (nearly flawless comedy)
3. 1408 (creepy as fuck, comical, good acting, unusual)
4. Planet Terror (completely insane and hilarious)
5. Sicko (highly amusing documentary)
Don't feel like going beyond 5, since this year has been pretty bad.
No idea about the best, but Die Hard 4.0 certainly wasn't it.
i would say the movie "Feast" was the best for me this year very amusing...
A
3. 1408 (creepy as fuck, comical, good acting, unusual)