well i dont know about pod farm but in gearbox (old pod-farm) i use the 1993 solo 100 head with the gain set to about 4, i comp my sound to about medium and use the tube screamer pedal in gearbox and im able to get a killer lamb of god sound to a well scooped machine head sound.
by far i vote the solo 100 the best virtual head in the whole package. often i dont even use the tube screamer setting. dont forget - more gain = more compression so you can often sound bigger with less gain. thats why eg: a fender deville would take your fucking head off if played at high volume compared to eg: my peavey 6505.