i dunno is settings....but from what i have heard from others....the only time they have ever used their gt6s with another amp was in 2003 on marshall jcm800s. i heard that their tone sucked. it really is the laney amps that do it. they have a nice dark, fat, and clear tone. without that, their notes wouldn't cut through the mix. i'm not sure of the exact settings. their guitars do a lot too. the prs custom 24s and their les pauls make a huge difference. there would be no way to get that creamy, dark, and crystal clear tone out of a jackson, or an ibanez. have you ever heard bootlegs of peter's live tone when he played his white jackson? it sucked....it sounded cheap (in my opinion)....overall, its not just the boss that does it. the boss just colors the tone that the guitars and amps put out. the laneys are set on the clean channel with the mids at around 8 or 9, and the bass and high end are on zero (from what i have heard)....then the boss does the rest. good luck..