since i got my sansamp psa-1 it's usually a blend of the DI and another track reamped through the sansamp.
for some reason i found that the whole splitting into low/hi track never really worked out for me. it always sounded like to different instruments regardless of where i set the crossover.
hence, i tend to use the sansamp track for the main tone, i.e. fat bottom end and sizzly, gained up highs, almost zero mids though.
this track will sound very brutal, but lacks a bit definition, so i'll blend in the DI track to give the notes some presence and cut.
other than that, both get bussed together, compressed, maybe some sub low enhancer for that really fat bass sound, and sometimes also limited. there might also be EQ, but only small adjustments to make the track sit better. i'll do more extensive EQ on the individual tracks, mostly carving space for the kick, adjusting the sub lows, and finding that 2-4k snarl which really cuts through.
the DI is also compressed and usually also limited, the sansamp with it's extra gain won't get that much compression though.
ah yeah, and often a multiband comp is used while reamping to make the bass sit better (andy sneap trick
)