I've never been much for crazy amp setups but there are some great amps that flat out stand alone. I never liked the marshall amps but for me Hughes and Kettner amps and Diezel amps can stand alone. I've played on those and gone from chugging rhythms to blaring solos on the same channel, no pedals, no changes, nothing. They're just such good amps and so powerful you can rip on them with no need for anything else. When it comes to other amps they're good but that's where you start getting into what you're asking about I think (5150s sound great but need lots of pedals and bullshit to truly unlock their potential, mesa IV's also can sound hugee but again need a lottt of tweaking). I dunno what you're really looking for but from what I've seen you play in a local band and have good gear and play shows, for that I'd say personally just get a great amp and keep it as simple as possible. Huge bands can get all sorts of crazy setups with blah routed to a million blah but it's really complex to deal with yourself so instead of going with all that just drop a good amount on an amazing tube amp, plug in, set up and blast.