say something about ... yourself!

[Mr.Sister]

by drinking water you're keeping your body hydrated because alcohol dehydrates you (and that's basically what a hangover is)

That's just one reason for a hangover, there are actually 3 more as far as I know:

-the destruction of proteins in your brain
-the lack of water follows also a lack of dietary minerals and glucose
and
-the intercalation of toxic acetaldehydes (which are found especially in cheap wines)

 

[Chromatose]

Actually all alcohol is broken down metabolically into acetaldehyde as one of the steps during its elimination. If you're drinking too much then the breakdown of alcohol can't keep up with the acetaldehyde dehydrogenase enzyme kinetics and you get the toxic buildup of acetaldehyde. Cheap wine would speed that accumulation up though I suppose, as they're not given time to age so still have a high level of acetaldehyde.

 

[WhiteBeastofWotan]

BAM, SCIENCE.

 

[derek]

Up in your fucking grill.

Love it.

 

[Mr.Sister]

Actually all alcohol is broken down metabolically into acetaldehyde as one of the steps during its elimination. If you're drinking too much then the breakdown of alcohol can't keep up with the acetaldehyde dehydrogenase enzyme kinetics and you get the toxic buildup of acetaldehyde. Cheap wine would speed that accumulation up though I suppose, as they're not given time to age so still have a high level of acetaldehyde.

Isn't just ethanol broken down to acetaldehyde? Cheap wine also contains other alcohols, which I actually ment in the first place, whose decay product are causing the hangover. (So I was wrong in my first post, sorry, I'm running a bit against the language barrier right now)

 

[Chromatose]

It's just a general alcohol metabolic pathway. Pretty sure you're right about the cheap wine thing though, it wasn't something that I had ever thought of before but I've recently been learning details of beer brewing science and all I know so far is that acetaldehyde is also produced by yeast in fermentation but over time is broken down as well, so I just took a random guess at the source.


edit:

pro-tip: Asians get red faces when they drink due to a mutation which causes a acetaldehyde dehydrogenase deficiency resulting in excess buildup of acetaldehyde

 

[Dead Winter]

Would that have something to do with drunks having red noses?

 

[Chromatose]

yep, that's the vasodilating effect of alcohol, just a lot more noticeable in asians.

 

[Liverslapper]

hhuuuuurrrhhhhh cheen chong gong

 

[Shpongled]

Sitting on my new balcony, enjoying the night time view with a bowl and a Racer 5 and my laptop and some tunes. I think this place is going to work out splendidly

 

[Captain Beard]

Actually all alcohol is broken down metabolically into acetaldehyde as one of the steps during its elimination. If you're drinking too much then the breakdown of alcohol can't keep up with the acetaldehyde dehydrogenase enzyme kinetics and you get the toxic buildup of acetaldehyde. Cheap wine would speed that accumulation up though I suppose, as they're not given time to age so still have a high level of acetaldehyde.

It's just a general alcohol metabolic pathway. Pretty sure you're right about the cheap wine thing though, it wasn't something that I had ever thought of before but I've recently been learning details of beer brewing science and all I know so far is that acetaldehyde is also produced by yeast in fermentation but over time is broken down as well, so I just took a random guess at the source.


edit:

pro-tip: Asians get red faces when they drink due to a mutation which causes a acetaldehyde dehydrogenase deficiency resulting in excess buildup of acetaldehyde

yep, that's the vasodilating effect of alcohol, just a lot more noticeable in asians.

You pulled a me...

 

[Chromatose]

I guess I learned something from all these years of SCIENCE

 

[E-bortion]

hhuuuuurrrhhhhh cheen chong gong

I just spit Dr. Pepper everywhere, you asshole!

 

[Psychonaut]

Hmm. Since losing all this weight I've gained almost a half inch in dick length.

And you're POSITIVE your brother didn't measure you wrong the first time?

 

[Krigloch the Furious]

 

[Tide In Mind Out]

About to go to my grandfather's visitation at the funeral home. He'd been in really bad shape since May and finally passed away last week. Sucks, but it's definitely a relief for him and the family.

Also, almost walked right into this guy the other day, eeeeeeeeeeeep!

 

[El Stormo]

Sorry for your loss, Cara.



... But spiders are damn awesome!

 

[Enemy242]

http://www.cracked.com/article_1946...ues-that-are-about-to-make-life-creepier.html

this is the kind of stuff i think about and dread every day, and pretty much why i love sci-fi and have a morbid fascination with our doomed future. basically all my sci-fi nightmares are coming true and i can't even imagine how fucked up the future will be when advertisements and government watching is so functional that we're all basically a 100% open book with no privacy. really fun and interesting article, in a morbid and dystopian kinda way.

 

[WhiteBeastofWotan]

I have to say that the domestic violence ad is a great use of technology. Pretty clever.

 

[neal]

well that article is pretty goddamn frightening