Read the remark on my last edit.
I have, and I still don't agree that believing in something that we know isn't true, whether you call it an informed belief or whatever, is the right option or the best shot. Sorry, but you're just deluding yourself.
Not exactly. It's just the most well-known experiment. Several experiments have been done after that, with more fruitful results. They are described in the article I quoted (and in the very fragment I also quoted as well).
Yes, "more fruitful". Still, right-handed amino acids, methane and ammonia, not a single protein, not even CLOSE. My argument stands undefeated.
The good old clockwork argument. That's the same as saying the human eye would have to be (intelligently) designed, because each of its components is inextrincable. Well, evolution and zoology itself refute this particular claim by showing progressively more complex visual apparata. The analogy is meant to show that there's no reason why the complexity of a primeval cell would be an obstacle for its generation out of simpler structures.
A dishonest use of analogy to attempt to prove a point you know you can't. Look, if you have the science to back up your claim, just present it and we'll be done with this whole discussion. Show me how a protein is formed from a mixture of chemicals, in a lab. A single one. You can't, so you come up with analogies. Show me how all the other structures needed for life could arise spontaneously from chemicals. I won't hold my breath, of course. More on why your human eye analogy fails when we talk about the genetic code needed to produce proteins.
A pretty artificial way to simulate the early earth. And again, the exact composition of the ancient atmosphere is still at debate - as implied by your own word, "speculated". There's much more to an environment than heavy gases, water and sparks. To quote another line from the wikipedia article,
More recent experiments by chemist Jeffrey Bada at Scripps Institution of Oceanography, La Jolla, Calif. were similar to those performed by Miller. However, Bada noted that in current models of early Earth conditions carbon dioxide and nitrogen create nitrites, which destroy amino acids as fast as they form. However, the early Earth may have had significant amounts of iron and carbonate minerals able to neutralize the effects of the nitrites. When Bada performed the Miller-type experiment with the addition of iron and carbonate minerals, the products were rich in amino acids. This suggests the origin of significant amounts of amino acids may have occurred on Earth even with an atmosphere containing carbon dioxide and nitrogen.
About a hundred elements in the periodic table, each might've played a role in this (although most probably there were just a handful). And given the fact that the earth is big enough for several combinations of relative concentrations to exist in different places, it wouldn't be that hard to find one 'just right'.
Straw man. I never even included in my response the difficulty imposed by carbon dioxide and nitrogen. And particularly, I chose the format of "even if... but in fact" for a cause. If it was possible to produce life in the lab, this "just right" condition could be easily demonstrated in the lab, alas it can't, and hasn't. Probability itself is against it, even if all chemical conditions are "just right".
That particular claim is also answered by the fragment I quoted.
That particular claim was actually just used to explain their experiment. Even so, the fragment you posted does nothing to overcome the burdens I presented with the rest of my argument.
That's wrong. Free oxigen wasn't available in the early atmosphere, as most of it was produced due to photosynthesis - i.e., after autotrophes (which are arguably more complex than heterotrophes and were most likely generated later) populated the planet.
Source:
http://www.ux1.eiu.edu/~cfjps/1400/atmos_origin.html
Sorry, but no. In the very link you posted there is another source of oxygen production, which is photochemical dissociation. But even so, as Dimroth and Kimberly explain (Dimroth, E. & Kimberley, M.M.,
Can. J. Earth Sci. 13 1161, (1976):
'in general, we find no evidence in the sedimentary distributions of carbon, sulfur, uranium or iron, that an oxygen-free atmosphere has existed at any time during the span of geological history recorded in well preserved sedimentary rocks'
(...)
'the sedimentary distributions of carbon, sulfur, uranium, and ferric and ferrous iron depend greatly upon ambient oxygen pressure and should reflect any major change in proportion of oxygen in the atmosphere or hydrosphere. The similar distributions of these elements in sedimentary rocks of all ages are here interpreted to indicate the existence of a Precambrian atmosphere containing much oxygen.'
(...)
'we know of no evidence which proves orders-of-magnitude differences between Middle Archaean and subsequent atmospheric compositions, hydrospheric compositions, or total biomasses.'
Again, this hypothesis that the primitive atmosphere was oxygen-free is just an attempt at producing an environment in which abiogenesis would be more possible. It is the a priori assumption that abiogenesis was true being used as the premise for the theories about the primitive atmosphere.
Now onto that 'catch-22': that's also a problem rising from over simplification of the conditions in the early earth. Here's an example of how it could've worked out:
http://www.sciencedaily.com/releases/2006/12/061208203049.htm
What? Did you even read what I posted? or did you just Google "oxygen, catch-22" and posted that link? I was writing about proteins and DNA being dismantled by UV, and you post:
"But researchers have long been puzzled as to how the cyanobacteria could make all that oxygen without poisoning themselves. To avoid their DNA getting wrecked by a ******yl radical that naturally occurs in the production of oxygen, the cyanobacteria would have had to evolve protective enzymes."
You are kidding, right? Over simplification? I'm talking about the difficulties of abiogenesis, and you're presenting a scenario with cyanobacteria already developed? And "struggling to evolve" enzymes to protect them from oxygen?? Check this quote from your article:
"This trickle of poison could then drive the evolution of oxygen-protecting enzymes in a variety of microbes, including the cyanobacteria." (emphasis mine, because it is just, again, a silly conjecture).
This answer of yours, along with another I will address soon, has made me abandon this discussion altogether. Sorry, but I don't have time for this.
And some models take ultraviolet light in place of lightning as the energy source for the chemical reactions. From
http://www.indopedia.org/Miller-Urey_experiment.html :
Conditions similar to those of the Urey-Miller experiments are present in other regions of the solar system, often substituting ultraviolet light for lightning as the driving force for chemical reactions. On September 28 1969, a meteorite that fell over Murchison, Victoria, Australia was found to contain over 90 different amino acids, nineteen of which are found in Earth life. Comets and other icy outer-solar-system bodies are thought to contain large amounts of complex carbon compounds (such as tholins) formed by these processes, in some cases so much so that the surfaces of these bodies are turned dark red or as black as asphalt. The early Earth was bombarded heavily by comets, possibly providing a large supply of complex organic molecules along with the water and other volatiles they contributed.
Again, Straw Man. I never said anything about the energy source for the reactions, and even if UV was used, oxygen would be needed to form the ozone screen and protect
proteins and DNA from the radiation. Catch-22.
Concentration of reactants affects speed of reaction, not whether or not the reaction occurs.
Surely you wouldn't want to mess with your chances. It's amazing how you're so blindly drawn to believe it must have happened, that no matter what the difficulties, you'll just wave at them, smiling, and turn a blind eye. My point is that those substances are NOT available, one of them is too dissolved to even have a use, and the other is stuck deep down in sedimentary clays and unreachable! But
even if you want to believe what you posted, you'd certainly wish the speed of the reaction was the fastest and as plentiful as possible, because those are, again, used just to assemble a simple amino acid, I am not talking about the other, more complex structures needed for life, such as, ahem, a protein.
Another issue of oversimplification. Read:
http://www.newscientist.com/channel...righthanded-amino-acids-were-left-behind.html
So a 100:1 mixture of L- and D-serine produces a solution made up almost entirely of L-serine, but so does a 100:99 mixture (Nature, vol 441, p 621).
Argh. It works BOTH WAYS. That's why the article concludes:
"Why there was a slight excess to start with is another question."
Again. The chances of producing right and left-handed amino acids are 50:50. As you are well aware, you need a LOT of such amino acid productions if you hope to, someday, produce a single protein. And, the longer you replicate an experiment with a 50:50 chance, the closer you'll get to an equal 50:50 proportion.
It's like playind head or tails. Play it once and you have a 100:0 proportion. Play it four times, maybe 75:25. Play it a billion times, ~50:50. That's a huge problem for you.
Again the clockwork argument. Spontaneous protein generation isn't observed - what we do observe are processes governed by nucleic acids assembling proteins out of existing amino acids.
Thank you. So you are saying a nucleic acid assembles proteins from amino acids? Now that's something we can agree on. Too bad you forget that in order for that nucleic acid to produce a protein, GENETIC INFORMATION is required in the first place. LOTS of it. If I still had patience for this, I could get home and give you a probability figure of that ever happening spontaneously, but I don't. Anyway, you leap 1000 miles forward to explain how something basic, to begin with, has come to be. Nice try, but at least you admit: "Spontaneous protein generation isn't observed".
Also note that in the Miller-Urey experiment, lipids (which are hydrophobic) were also formed. Coacervation(
http://en.wikipedia.org/wiki/Coacervate) is proven to happen spontaneously in certain conditions, providing an appropriate framework for nucleic acids to translate into protein. Also let us remind that:
A peptide bond can be broken by amide hydrolysis (the adding of water). The peptide bonds in proteins are metastable, meaning that in the presence of water they will break spontaneously, releasing about 10 kJ/mol of free energy, but this process is extremely slow.
http://en.wikipedia.org/wiki/Peptide_bond
So, water is hardly an issue here.
Red herring? You haven't provided any scenario for nucleic acids ever translating anything into anything, and you're throwing in coacervation? Also, water is still an issue. As I said earlier, it tends to break not only amino acids, but also proteins. And now you write it yourself. It doesn't matter if the process is slow, as I said, if you need billions of years for the process to happen, they will break.
Clockwork argument. See above.
I wasn't aware everything in abiogenesis, no matter how unproven, could simply be dismissed with "clockwork argument". Hm. It must require lots of faith to believe in it, indeed.
We're discussing mainly on sources here, as none of us is an expert in biology. Therefore, quoting a physicist to illustrate an alledged 'impossibility' (although that quote didn't prove impossibility. All he said was there was no evidence, which's not correct in any case). Being partial to ID and not being an expert makes his opinion in this discussion pretty much void.
No, your prejudice makes it void. His conclusions are still perfectly valid. You may fret as much as you want, but unless you can replicate the origin of life in a lab, and you can't because chemistry itself is a huge burden, you can't go about telling everyone life just came to be spontaneously. That's bad science.
That's the most common misconception about evolution by most creationism defenders. The process is guided by natural selection, so proteins aren't generated 'at random'. The solution space being large doesn't imply in the no-existence of an efficient way to select an optimal solution. In fact, evolution in this way (and the grammar-like structure of proteins and nucleic acids) is very similar to branch-and-bound approximation algorithms used to solve certain computational problems. Problems for which the solution space is
extremely large (larger than, for example, combining peptides) can be solved very efficiently in this way.
Read:
http://www.skeptics.com.au/articles/dawkins.htm
In particular, read his introduction to information theory and then the section "The Genetic Book of the Dead". The environment feeds information which harness the randomness creationists so dearly hold as an argument to their side.
This is it. To quote Dawkins is... I just don't know what to say. The guy knows ZERO about information theory, and his WEASEL program proves that for anyone that wants to see. The kind of intellectual dishonesty that is required for someone to present that as proof of information-building via natural selection is incredible. It's really incredible. By the way, a little gossip. Did you see Dawkins running from Dinesh when Al-Jazeera invited him for a debate? Turns out Dawkins didn't know who his opponent would be, and when they revealed it to be Dinesh, the poor old man insisted on a format in which he could not be rebutted.
Anyway, we could start a whole new discussion on Information Theory here, which is a subject I actually love and know a bit about, since I also coursed Computer Science, but I won't because it is simply not relevant AT ALL to the subject at hand and I don't have time. Let me just say you are mixing things up really badly here. Natural selection does NOTHING to help with abiogenesis. NOTHING. The problem isn't in "amino acids which are not fit for survival and replication", or proteins, or DNA for that matter. That would actually be quite an absurd proposition. Dismissing everything as a "clockwork argument" leads to this, confusion about the roles of each process in the whole of evolutionary theory. Abiogenesis HAS to be taken as a random process, PERIOD. Every step of it is random, there's no "buts" about it, and this is simply science.
You could start ANOTHER conversation on how GENETIC INFORMATION could be altered by mutations to produce different sets of proteins. That's a WHOLE different story. Don't mix things up. We are talking about abiogenesis. It isn't a guided process at all. It is random. Present how it happened. Replicate it in the lab. It is THAT simple.
That's just a version of that joke - you have a swiss cheese, full of holes. The more cheese, the more holes. The more holes, the less cheese. Therefore, the more cheese, the less cheese. Given a larger sample the frequency of the outcome of any event tends to stabilize.
http://en.wikipedia.org/wiki/Law_of_large_numbers
Poor analogy. Read it again, it has nothing to do with your semantic paradox. It's not a paradox at all, it's just that water makes it difficult for proteins to form, and you need time and water. It's simple as that.
Clockwork argument *again*?
Just show how it happens. Please. Show us the science:
- DNA
- Proteins
- Cell membrane
- Cell wall
Show us the experiment. Please, where is the science? Should we start calling science "clockworklol"?
And let me say this one more time. A laboratory doesn't faithfully replicate the early earth nor the time it took for random events to occur over billions of years.
An unguided process needs billions of years to occur. Because it's subject to random, uncontrolled events. That's why you need time, not because the chemical reactions itself need time, its because the odds are so overwhelmingly against abiogenesis, that you need all the time you can get for a "miracle" to happen. In a lab, it's different. If it could, it would be replicated.
Well, first: "Life arising out of nowhere" is a pejorative definition which takes the form of a slippery slope fallacy to try to discredit abiogenesis. Secondly, you haven't argued against abiogenesis - you have argued against the evidence and knowledge we (well, biologists) think we have about the processes governing it.
Don't call it that, if it uneases you. It's not what you call it that discredits it, it's the lack of objective evidence that does the job. Unfortunately it is preached as being something certain and taken for granted, when scientists have absolutely no clue about how it happened. That is the fact. You are waiting for the magic bullet, you need it but it hasn't come. All you have are chemical process that go AGAINST it, so you just cling to faith that "you might be wrong", even though the processes themselves are very well estabilished.
Then I can hardly see how it's against probability (you haven't shown that)
I have, let me repeat it then, the whole of it, even though it's only about proteins:
Since you're specially picky with the authors I quote (and let me say there was nothing wrong with Hoyle's citation, firstly because it wasn't meant as authoritative source, but merely to illustrate the impossibility of abiogenesis, and he stands correct on what he said, and secondly because being partial to ID should not mark him as demeritorious at all, unless one reads such a scientist with partiality), let me pick a quote from Dr. Monroe Strickberger instead, the author of the college textbook Evolution:
"Thus, if we randomly generated a new 100-amino-acid-long sequence each second, we could expect such a given enzyme to appear only once in 4x100*122 years!"
Since you have presented that abiogenesis must have happened 4.4 billion years ago, and that it's shown that it would take MUCH longer to form only ONE enzyme necessary to life, the theory of abiogenesis fails. But Dr. Strickberger continues:
"In terms of the volume necessary to generate all such possibilities, the difficulty appears just as immense: If an entire universe, 10 billion light years in diameter, were densely packed with randomly produced polypeptide... the number of such molecules 10*105 would not equal their 10*130 possibilities".
or "against the very nature of life" (you haven't show that either).
I have. I've shown the chemical processes that work against the formation of proteins. That alone suffices. If I had to paste that again in here, I'd have to repeat my entire argument.
The point is that abiogenesis, however it may have occurred, is the only sensible (i.e., not involving ad hoc absolutely non scientific unsupported by evidence and refuted by logic supernatural beings) scientific choice - because it's such a broad term. Even if all the experiments we (biologists) have done turn out to be wrong, and generation of complex molecules in the way we consider most likely couldn't occur at all, they'd have to occur in some way, and unless some really heavy evidence pops out of the blue, it'll have to be abiogenetic - or you're relying entirely on an enormous, like you say, leap of faith.
In bold, your leaps of faith exposed.
I now leave this discussion. Goodbye.