what is your tuning & strings gauge ?

PRS Custom 22: .012, .017, .024p, .036, .050, .060 in A# F A# D# F A#
PRS SE One: .012, .017, .024p, .036, .050, .060 in A# F A# D# G# C#
PRS Mushok Baritone .013, .018, .024p, .042, .054, .072 in A E A D G A

I'm weird though, I like an odd combination of tight and loose, even for different tunings. In drop A, I get along better with tighter strings on the baritone for some reason. It's all a feel thing, I suppose.
 
25.5 scale 7's in G# -> 13 to 72
24.7 scale 6's in C#/drop B -> 13 to 62 (my favourite string gauge/tuning)
25.5 scale 6's in E to C# -> 12 to 52

I can span a lot of tunings doing it like this.
 
Drop D
Ibanez SZ2066 with EMG 81/85
Sometimes I buy a 7 string set and use the bottom and top 3, so I'm going 9-54 or something like that. But they're a it expensive, so I think I'm gonna move to Dunlop 10-52's to save some cash.
 
Stinnett C6 custom and Schecter C-1 Stealth (TOM bridges) - 10-52 (10, 13, 17, 28, 38, 52)
Fender Telecaster - 10-46 (standard guages)

All gtrs in E standard. I use the heavier bottom strings on the TOM loaded guitars because I pick things out of tune more often on those due to the bridge being higher off the body, and the relatively thinner strings on the Tele help to retain some of that classic Tele smack/twang that I've nearly negated with humbuckers.
 
ESP horizon nt-II

Drop A#

.70 .52 .36 .22p .17 .13 D'addario.

make sure you re-adjust all the relevant hardware on a string guage increase. fairly obvious to most of you but i know of people who run massively dropped tunings with fatter than normal strings and the guitar is still set up for standard!
 
9-46+59 on my Ibanez RG7421 (7 string guitar)
9-42+56 on my Schecter Hellraiser C-7

When I played 6 strings, it was E standard. I still use the same tuning now, just with the added low B string.