When people get there damn facts misconstrued. This particularly happens with most religious people I've dealt with. GOD FORBID you have an intelligent discussion with someone about the merits of an ethical system that doesn't involve God (not to say that God doesn't exist, just that a system can exist independently).
Also, people who refuse to change their positions on anything, especially in light of evidence. I love science, I adore it - but people don't realize that science isn't about proving that YOU are right about what you are talking about. Science is indiscriminate, and merely exists to point us in a non fallacious direction. So when someone holds a belief that is backed up by information that is totally false and refuses to relinquish that stance for whatever reason.... that infuriates me. There is nothing wrong with being wrong, we are all wrong at some point!
Also, when it comes to physical abuse... be it man, woman or tiny animals, I want to rip the throat out of the perpetrator with my fucking teeth as I bury my knuckles into their kidneys, ribs and eyes. I have no remorse for people who commit such crimes.