I only PC-game rarely and casually, but my wireless mouse works fine for it, and since I use a laptop where all my cables are snaking across my desk, each one I can cut down on is WELL worth the sacrifices that I don't perceive at all (the only one I can think of is batteries, which I swap every 1 1/2 months or so). And we're talking about mice here people, jesus tap-dancing christ...