Honestly, the whole "no inventory screen, magic room where you walk up and equip things" concept is probably going to ensure I never play it.
I've done nearly everything in New Vegas already, except lame little quest not worth mentioning and to finish up the main story line. I think it's GOTY, a notch above Mass Effect 2 if only for the higher replay value (and the fact that it wasn't practically a shooter). There was a certain part of the main quest that was so spine chilling and creative I had to pick my feet off the floor and back the hell up with my gun ready to mash the trigger for dear life if it moved any closer to me.