Yeah, just make damn well sure your diet is on point by doing the calculations and dont overdue it. 5 days/week of heavy cardio on a caloric deficit can get you feeling like shit REALLY fast.
If you want to stick to weights mostly, stick to 10-12 rep range, and cut your rest periods between sets to 45 seconds between sets and 60-75 seconds between excercises. Workouts should last no longer than 30 minutes in that fashion because of the cut in rest time, and often considerably less than that even. Then go hop on the treadmill/eliptical/whatever for a good 15-20 minutes.
Always listen to your body...if its telling you to slow down and you feel the fatigue setting iin and the achiness, take a day off.
If possible, if you can hit the cardio upon waking up from slumber, on an empty stomach, even the better.