Did IF have any song which infiltrated mainstream radio there? I'm not saying I never heard screaming in a mainstream radio, but it was Schrei from Tokio Hotel, so there's that.
And at this point, I doubt IF would give any fuck. Like... ANY. Maybe they did stuff back in the day to cater to a wider audience, to skyrocket their career, but I honestly can't see them caring much about it anymore. By now, In Flames for them is probably a side project, where most of the money is from touring, and even if they release a polka album, they can still tour with their older songs.