Oh god. Uuuhh... fuck. The pressure!
First things that come to mind (One issue each, so you can see if you want to follow along with it.) :
Amazing Spider-Man (1963) #648
Avengers (2012) #1
Avengers Academy (2011) #1
Black Widow (2013) #1
Captain America (2004) #1
Daredevil (1998) #26
Deadpool (1998) #1
Fantastic Four (1963) #570
Hawkeye (2012) #1
Indestructible Hulk (2012) #1
Iron Man (2006) #1
Journey into Mystery (2011) #626
Marvels (1994?) #1
Punisher (2000) #1
Runaways (Vol. 1/2003?) #1
Secret Warriors (2008) #1
Thor (2007) #1
X-Men get their own category because there are so damn many.
New X-Men (2001) #117
Astonishing X-Men (2004) #1
Uncanny X-Men (1963) #500
Uncanny X-Force (2011) #1
Wolverine & the X-Men (2011) #1
I love recommending comics.
(Also, MDCU's reader kinda blows. One of the reasons I ended my subscription. Just a warning.)