Cool guys, here's the chain since you asked. I actually had the mids on '1' on the amp the whole time, but funny stuff happens when you go this route. I agree there are too many flat mids in mine, but it was inevitable in the method I used. There were 2 tones, 1 for each pair of guitars.
Tone 1: Red Eye > Custom Tubescreamer > Bugera 6260 Lead Channel > Speaker Out > Countryman Type 85 > Millennia Origin > Catharsis Pres 8
Tone 2: Red Eye > Bugera 6260 Lead Channel > Speaker Out > Countryman Type 85 > Millennia Origin > Catharsis New impulse
Tone 1 was doing the smooth stuff, whereas 2 did the grinding and 'crunch'.
Now I'm still wondering whether I permanently damage the output transformer by not using a load! haha.
Agree with lolzgreg re: needing a mix. Having at least a bass guitar to add in is a tad crucial in getting the lows to sit right.