There are different kinds of nerve cells. I'm most worried about the motor neurons. But it is pretty bad for your brain. If I sniff a lot of rubber cement, I will get a ten minute high with a hard to describe full body warmth, and I will be numb. However, for the next week, I will be stupid. I won't be able to think about anything. That shows how much damage it causes. Luckily, most of it is repaired. However, I am sure repeated use will make me like that permanently. I am not as smart as I used to be. There is both short term and long term brain damage. Most is not permanent, but neurons never grow back the same. They always mutate. I actually wonder if this brings a risk of brain cancer. Some types of inhalants are proven to cause lung cancer.